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The effect of ultraviolet (UV) radiation on the infectivity of Taenia taeniaejormis eggs was observed. The eggs were exposed to various UV doses and orally inoculated to rats. The number of cysts and lesions decreased dose-dependently, and neither cyst nor lesion was observed from rats infected with eggs exposed to a total dose of 2,880 mJ/cm or more. For evaluation of protective role of embryophore against UV radiation, the onchospheres with/without embryophore were exposed to UV radiation. Remarkably lower numbers of cysts and lesions were observed in rats inoculated with eggs which were exposed to a total dose of 30 mJ/cm2 or more after removal of embryophore. These results suggested an importance of the protective function of the embryophore in the protection against UV radiation.